PlexusDx Reviews 

90
•
TrustScore 4.5 out of 5

4.4

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Review summary

Created with AI, based on recent reviews

Considering 86 reviews, reviewers overwhelmingly had a great experience with this company. Customers frequently praise the fast shipping, seamless delivery, and the incredibly streamlined process for getting started with their medical prescriptions. People consistently note that the support team, care members, and medical staff provide prompt, helpful guidance and clear communication throughout the entire health journey. However, some reviewers were not happy with occasional order errors, delivery delays, or prescription mistakes that required extra time and effort to resolve. A few other people also felt that the initial dosage increases were too slow or experienced frustrating communication gaps with the clinical support team.

What people talk about most

Product

Customers had positive experiences with product, reporting significant weight loss, a noticeable decrease in... See more

Customer service

Reviewers mention positive feedback about customer service, highlighting that support agents and care teams... See more

User experience

Users describe positive interactions with user experience, highlighting how easy it is to navigate the... See more

Service

Clients share positive opinions on service, highlighting quick communication, fast response times, and... See more

Delivery service

Consumers find delivery service to be positive, highlighting extremely quick shipping and reliable... See more

Reviews shaping this summary

Rated 4 out of 5 stars

I am a little frustrated that my prescription was made out to stay on the same dose for 12 weeks so that is why I gave 4 stars. I am really happy with my meeting with a doctor who is hoping to help me... See more

Company replied

Rated 5 out of 5 stars

The team has been so helpful and responsive! I had a great meeting with the medical director, all of my questions were answered. PlexusRX has made me feel supported and excited along this journey! Dow... See more

Company replied

Rated 5 out of 5 stars

My experience with PlexusDx has been really fantastic. Questions answered within minutes and first dose arrived next day. They are really on top of things and J would highly recommend them. I did loo... See more

Company replied

Rated 5 out of 5 stars

What started off a little bit rocky turned into a phenomenal experience. I had placed an order right before a major US holiday causing a shipping Delay. The COO, Adam, MADE SURE to make it right. He p... See more

Company replied


Company details

  1. Fitness and Nutrition Service
  2. also in
  3. Vitamin and Supplements Store
  4. Wellness Program

Written by the company

PlexusDx is a science-driven health testing company that empowers individuals to make more informed, personalized health decisions using at-home genetic testing and blood tests. PlexusDx combines DNA analysis and lab-based blood biomarkers to deliver actionable insights across nutrition, metabolism, methylation, hormones, cardiovascular health, inflammation, longevity, and overall wellness. All tests are easy to complete from home and processed by certified laboratories, with results delivered through a secure digital health portal. A core differentiator of PlexusDx is its ability to use a customer’s genetic and blood test results to personalize diet and meal plan recommendations. Rather than generic nutrition advice, PlexusDx analyzes key genetic pathways and blood markers to help guide food choices, dietary patterns, and lifestyle strategies aligned with an individual’s unique biology. PlexusDx also leverages genetic and blood data to provide personalized supplement recommendations, helping customers better understand which nutrients may support their health goals based on their results. These recommendations are designed to complement diet and lifestyle decisions—not replace medical care—and are presented in a clear, easy-to-understand format. PlexusDx is especially known for its advanced Genetic Methylation Test and Methylation Blood Tests, which focus on critical biochemical pathways involved in energy production, detoxification, nutrient metabolism, and cellular function. By pairing genetic methylation insights with blood-based validation, PlexusDx offers a deeper, more complete view of methylation-related health factors. Results are delivered through the PlexusDx Results Portal, where customers can view their reports, personalized insights, and recommendations in one centralized, secure platform. PlexusDx supports HSA and FSA payments and is committed to transparency, data accuracy, and exceptional customer support. Whether you’re seeking personalized nutrition guidance, deeper insight into methylation pathways, or proactive wellness testing, PlexusDx provides trusted, data-driven tools designed to support informed health and lifestyle decisions.


Contact info

4.4

Excellent

TrustScore 4.5 out of 5

90 reviews

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1-star

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Replied to 100% of negative reviews

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4.4

All reviews

(90)

90 reviews in the last 12 months

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Rated 5 out of 5 stars

PlexusDX review

I have been very impressed with the care and attention that this company provides to its customers and the guidance rendered. Their delivery of service is superior in every way and the attention to detail is very helpful to a first-time user of their products.
I highly recommend their services. I especially enjoyed the guidance in the usage of the medication provided by Dr. Jayden Lee.

September 9, 2026
Unprompted review
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Reply from PlexusDx

Thank you for the kind words Paul. This is why we got into this business. -Adam Valentine, COO

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Rated 5 out of 5 stars

So far so good

So far so good, the process what easy and shipping was prompt. No complaints

September 4, 2026
Unprompted review
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Reply from PlexusDx

Thank you Channon. We started this company to help people. If you ever have feedback, we listen. Our biggest company improvements have come from our customers. - Adam Valentine, COO

Rated 5 out of 5 stars

Wonderful customer service with on time…

Wonderful customer service with on time prescriptions. I have no complaints and have recommended this company to many of my friends and associates. A big thank you to everyone involved.

September 8, 2026
Unprompted review
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Reply from PlexusDx

Thank you Rhonda! We are always here to help you on you journey. - Adam Valentine, COO

Rated 5 out of 5 stars

This company builds on trust

I'm updating to let you know how important is for a company to respect your wishes into convey support and comfortability even in a not so favorable situation. Due to the fact that they showed care and concern, I continue to strive to let them correct the situation which they did and now I am super happy because I am going to receive the medicine that I am to get with my GLP -1 journey . They even refunded me for the unsatisfactory dosages that they had prescribed. Absolutely a beautiful company to have help you

September 5, 2026
Unprompted review
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Reply from PlexusDx

Christina, I apologize for your horrible experience. We failed you. I have spent the morning reviewing your account and interactions on our platform.

1) You did nothing wrong and did not deserve this.
2) Be on the lookout for a confirmation email, but we are refunding your first order and the current.

I am taking the steps to correct this issue internally with all parties associated with your interactions. Myself and other founders got into this business to help people (one of our core values) and that standard was not lived up to.

Once again, I apologize for the teams' actions and please be on the lookout for an email confirmation. - Adam Valentine, COO

Rated 5 out of 5 stars

Every step to get started was easy

Every step to get started was easy. My Dr. Has showed care during the last 4 weeks as i transition to this new lifestyle. Great communication from all the staff. Their product works wonderfully! No more food noise or craving. Have total control over sweets now and other carbs.

September 6, 2026
Unprompted review
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Reply from PlexusDx

Thank you Donna! I will let the team know - Adam Valentine, COO

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Rated 5 out of 5 stars

The process to get started is SO easy

The process to get started is SO easy! All my questions were answered and the support along the journey is consistent and timely. Refills and delivery are seamless!

September 5, 2026
Unprompted review
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Reply from PlexusDx

Rabeka! Thank you for the review and I have passed this off to the team over the holiday weekend. They work hard maintaining our provider and pharmacy relationships so this experience is the standard. They continue to fight hard for lower costs and a more efficient experience. - Adam Valentine, COO

Rated 5 out of 5 stars

So far, so good.

A relatively quick process for consideration in regard to starting at a higher dose (I was taking a higher dose than the standard 2.5mg starting titration when I messaged about purchasing from PlexusDX).

I appreciate the fact that they made sure the script was valid before I was able to purchase the 6 month plan.

I was previously using AltRx as it was cheaper but they used a common subcutaneous injection reaction (a red splotch at the injection site that lasted, at most, an hour) as a reason for discontinuing my prescription with them and even with my primary care doctor providing their ‘okay’ to continue, they discontinued it. I assume it was because of the lawsuits from the FDA that they discontinued my script.

And I digress, while PlexusDX is a little more expensive than some other telehealth companies, I think the fact that there are no lawsuits or FDA concerns surrounding this company is one of many reasons that paying more, is worth it.

It was sent and delivered quickly and was properly temperature controlled when it arrived (ice pack was still active). Everything was packaged nicely with clear instructions.

So far, it’s been a pleasant experience and I intend to continue to use PlexusDX for the entirety of my weight loss journey going forward.

September 5, 2026
Unprompted review
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Reply from PlexusDx

Ciara, thank you for the glowing review. I sent this off to the team. They are working hard maintaining and improving out pharmacy network so your cost continues to lower. We started (and still are) as an at-home genetic testing company and feel you should always expect more from your GLP1 provider. - Adam Valentine, COO.

Rated 5 out of 5 stars

Very Good Experience!

I’ve had a very positive experience with Plexus Dx. The communication and customer service are excellent. I’m happy with the quick shipping and GLP with great results! I love that it’s not a subscription company and would highly recommend!

September 4, 2026
Unprompted review
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Reply from PlexusDx

Thank you Sarah! This is great to hear because we wanted to give every customer one less financial headache to worry about. - Adam Valentine, COO

Rated 5 out of 5 stars

Happy!

I have had a wonderful experience. I am always being asked if I have any questions, how is it going and do I have any concerns. Getting the medication was so easy and it arrived quickly. I am so happy with my experience 😊

September 3, 2026
Unprompted review
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Reply from PlexusDx

Thank you Kathy! I have sent you review to the team. They work very hard maintaining our provider and pharmacy relationships so this experience is the standard. It's a team effort. - Adam Valentine, COO

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Rated 5 out of 5 stars

Very Prompt, great effective product

My analysis and order were very promptly fulfilled for PT-141. The peptide formulation and dosing worked VERY well for me, really meeting/exceeding expectations.

August 21, 2026
Unprompted review
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Reply from PlexusDx

🤝🏻 (handshake emoji) - Adam Valentine, COO

Rated 5 out of 5 stars

Very impressed with how they handled my concerns!

I initially had a rough start with PlexusDx regarding my GLP-1 prescription, but I am very impressed with how the situation was handled. The CEO of the company personally reached out to me, listened to my concerns, and immediately took care of the issue.

That level of personal attention and customer service really says a lot about a company. Problems can happen, but what matters to me is how a company responds—and PlexusDx went above and beyond to make things right.

I’m very thankful that the CEO took the time to contact me personally and resolve everything so quickly. It completely changed my experience, and I truly appreciate the care and attention I received.

June 2, 2026
Unprompted review
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Reply from PlexusDx

Thank you Christina. Everyone, including leadership, is hands on with all customer interactions. I will make sure to give Jay a gold star.

All kidding aside, customer issues have lead to our biggest improvements, which help others after them. Any feedback is valuable and you're helping others without know it. - Adam Valentine, COO.

Rated 5 out of 5 stars

Great Customer Service and Support

Clear and concise communication throughout the process with real results from the products used. Shipping is fast and easily tracked. Overall, a great experience.

September 2, 2026
Unprompted review
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Reply from PlexusDx

Hey Jim, thanks for making our Wednesday. We are always listening to customer stories and how we can improve. - Adam Valentine, COO

Rated 5 out of 5 stars

Great company/great product

Excellent customer service, super fast shipping, and so far, amazing results. I love the microdose as the food noise is gone, I’ve lost 4 pounds in the first week, and I have zero negative side effects.

August 31, 2026
Unprompted review
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Reply from PlexusDx

Lyndsay! This is great news. We got into this business to help people. I will share with the team. - Adam Valentine, COO

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Rated 5 out of 5 stars

Pharmacy review of side effects

Helpful review of medication with pharmacy review of side effects, with easy information. Easy to get an appointment

August 31, 2026
Unprompted review
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Reply from PlexusDx

Thank you for sharing. We pride ourselves on responding as fast as we can. And yes, I do see the irony of saying that and responding 2 days later :) - Adam Valentine, COO

Rated 1 out of 5 stars

They sent me placebo!

It took almost 2 weeks to receive my glp-1 medication. The vial I received was placebo in my opinion, Or at the very least, diluted and completely ineffective. I asked for a refund and to send the remainder of the vial back. They said no. They could’ve offered a replacement or something, but nope just money wasted. They offered competitive pricing, but buyer beware. I ordered from altRX who then sent me the real deal. Lost 20 lbs in 1st month.

August 5, 2026
Unprompted review
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Reply from PlexusDx

Hi Allison (I sent you an email already). I’m sorry that PlexusDx fell short of what you expected. You provided us with a previous prescription that clearly states you are taking the maximum dosage clinically allowed.

Our provider really should have communicated that the product you signed up for was for microdose, which has a maximum dosage of less than 2.5mg a week and really meant for patients either just starting out with GLP-1's, concerned about side effects, or just looking to lose 1-2 pounds a week.

It is no wonder that you felt like the drug was ineffective.

As a courtesy, I’m expediting a full refund of your purchase. There is nothing further you need to do, and you do not need to return the remaining medication. Once the refund has been processed, it may take a few business days for your bank or card issuer to reflect the credit.

We take patient feedback seriously, and I’m also sharing your concerns internally so we can review the experience from start to finish.

I’m sorry we weren’t able to provide the experience you were hoping for and I am happy you were able to find the medication that's right for you.

-Jay Hastings, CEO

Rated 5 out of 5 stars

Onboarding was smooth and I received my…

Onboarding was smooth and I received my peptides quickly, I have been using them for over a month now and am seeing results that I was looking for, thanks PlexusDX!

August 27, 2026
Unprompted review
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Reply from PlexusDx

Thanks Thom! We are happy you're seeing results! - Adam Valentine, COO

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Rated 4 out of 5 stars

It was easy to sign up

It was easy to sign up, no fuss. No labs required, low cost, easy text services and email communication. Only down side compared to other companies that I have tried is that the doses are to low and too slow to increase for effectiveness.

August 26, 2026
Unprompted review
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Reply from PlexusDx

Thank you for the feedback Angela. I will flag this for your provider. If there is anything else we can do to make your experience better, please let us know and email support@plexusdx.com

Rated 3 out of 5 stars

Communication is Lacking

*Edited rating from 1 to 3 Stars due to the company refunding and trying to make this right which is greatly appreciated* I still do not have a resolution to my original issue and I am still experiencing trouble getting someone to just look at my account to give me straight answers, waiting five days+ for a refill approval when it is supposed to take 24 hrs, etc. I would have rather the problem fixed than a refund.

Original review:
Great onboarding, super easy process to get a prescription. I recommended to a few friends. Provider went up on my dosage for my first refill. But when my refill arrived, it was the lower starting dose, not my prescribed dose. I immediately messaged customer service. They said to just double my dose but then when I asked for clarification a nurse said to just hold my dose. Super frustrating because I didn't receive what I paid for and feel like I have wasted money and time (no results). Going in circles for weeks with customer service trying to get a resolution. They said this week if I would just fill out my intake form for ANOTHER refill that they could fix the problem. I should have known better because still no resolution to my issue.

Feels like I am just trying to get help from AI bots and the processes and procedures are a mess.

August 21, 2026
Unprompted review
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Reply from PlexusDx

Hi Melissa, I took a look at your account, and I wanted to let you know that I just submitted a refund request to cover both of your charges - please allow a few business days for the funds to clear your bank. In addition, I have reached out directly to your prescribing provider to provide you the written instructions regarding this issue. This question should of been answered weeks ago by the clinician and I apologize that you had to go through all this frustration to get a simple answer, especially since the vial and concentration are exactly the same. Please check your email. I am sorry we failed you here. - Jay Hastings, CEO.

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